Organochlorine recovery from small adipose samples with the universal trace residue extractor (unitrex)

Preparing adipose tissue for the determination of certain lipid soluble compounds, particularly pesticides and polychlorinated biphenyls is labor intensive. The methods used generally involve the coextraction of lipid and analyte from the fat, followed by cleanup procedures designed to isolate the a...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 1987-11, Vol.39 (5), p.848-856
Main Authors: HEAD, S. L, BURSE, V. W
Format: Article
Language:English
Subjects:
Adipose Tissue - analysis
Aroclors - analysis
Biological and medical sciences
Female
Humans
Insecticides - analysis
Lipids - analysis
Medical sciences
Pesticide Residues - analysis
Pesticides, fertilizers and other agrochemicals toxicology
Toxicology
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Summary:Preparing adipose tissue for the determination of certain lipid soluble compounds, particularly pesticides and polychlorinated biphenyls is labor intensive. The methods used generally involve the coextraction of lipid and analyte from the fat, followed by cleanup procedures designed to isolate the analyte before analysis. Forced volatization uses heat and gas flow to separate the more volatile chlorinated compounds (subsequently trapped by a scrubber) from the less volatile lipids. The most recent commercially available form is the Universal Trace Residue Extractor (unitrex). This apparatus seemed to require a minimum amount of analyst's time and, with its capability for handling 10 samples simultaneously, offered the possibility for high sample throughput. This study evaluated Unitrex by comparing it with four analytical procedures with regard to: recovery of added analyte (in vitro); recovery of analyte (in vivo) from human breast fat; and efficiency of lipid removal.
ISSN:0007-4861
1432-0800
DOI:10.1007/BF01855865