The effects of aerobic exercise training at two different intensities in obesity and type 2 diabetes: implications for oxidative stress, low-grade inflammation and nitric oxide production

Aims To investigate the effect of 16 weeks of aerobic training performed at two different intensities on nitric oxide (tNO x ) availability and iNOS/nNOS expression, oxidative stress (OS) and inflammation in obese humans with or without type 2 diabetes mellitus (T2DM). Methods Twenty-five sedentary,...

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Bibliographic Details
Published in:	European journal of applied physiology 2014-02, Vol.114 (2), p.251-260
Main Authors:	Krause, Mauricio, Rodrigues-Krause, Josianne, O’Hagan, Ciara, Medlow, Paul, Davison, Gareth, Susta, Davide, Boreham, Colin, Newsholme, Philip, O’Donnell, Mark, Murphy, Colin, De Vito, Giuseppe
Format:	Article
Language:	English
Subjects:	Aerobics Biomedical and Life Sciences Biomedicine Body mass index Cytokines Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology Exercise Fitness training programs Glucose Human Physiology Humans Inflammation - blood Inflammation - metabolism Inflammation - physiopathology Insulin resistance Male Males Middle Aged Muscle, Skeletal - metabolism Musculoskeletal system Nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase Type I - blood Nitric Oxide Synthase Type I - metabolism Nitric Oxide Synthase Type III - blood Nitric Oxide Synthase Type III - metabolism Obesity Obesity - blood Obesity - metabolism Obesity - physiopathology Occupational Medicine/Industrial Medicine Original Article Oxidation Oxidative Stress Physical fitness Sports Medicine Tumor necrosis factor-TNF
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