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A study of adaptation mechanisms based on ABR recorded at high stimulation rate

Highlights • The fast and slow adaptation mechanisms are studied for the first time in humans through the separated responses methodology. • Both fast and slow mechanisms of adaptation are present in all subjects, which is consistent with previous animal studies based on spike rate. • The morphology...

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Published in:	Clinical neurophysiology 2014-04, Vol.125 (4), p.805-813
Main Authors:	Valderrama, Joaquin T, de la Torre, Angel, Alvarez, Isaac, Segura, Jose Carlos, Thornton, A. Roger D, Sainz, Manuel, Vargas, Jose Luis
Format:	Article
Language:	English
Subjects:	Acoustic Stimulation - methods Adaptation Adaptation, Physiological - physiology Adult Auditory Brainstem Response (ABR) Auditory Threshold - physiology Electroencephalography Evoked potentials Evoked Potentials, Auditory, Brain Stem - physiology Female Humans Interstimulus interval (ISI) Male Middle Aged Neurology Randomized stimulation and averaging (RSA) Reaction Time - physiology
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container_title	Clinical neurophysiology
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creator	Valderrama, Joaquin T de la Torre, Angel Alvarez, Isaac Segura, Jose Carlos Thornton, A. Roger D Sainz, Manuel Vargas, Jose Luis
description	Highlights • The fast and slow adaptation mechanisms are studied for the first time in humans through the separated responses methodology. • Both fast and slow mechanisms of adaptation are present in all subjects, which is consistent with previous animal studies based on spike rate. • The morphology of the ABR is not only influenced by the stimulation rate, but also by the distribution of the jitter, and by the sequencing of stimuli.
doi_str_mv	10.1016/j.clinph.2013.06.190
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subjects	Acoustic Stimulation - methods Adaptation Adaptation, Physiological - physiology Adult Auditory Brainstem Response (ABR) Auditory Threshold - physiology Electroencephalography Evoked potentials Evoked Potentials, Auditory, Brain Stem - physiology Female Humans Interstimulus interval (ISI) Male Middle Aged Neurology Randomized stimulation and averaging (RSA) Reaction Time - physiology
title	A study of adaptation mechanisms based on ABR recorded at high stimulation rate
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