The utility of facial nerve amplitude and latency ratios in predicting postoperative facial nerve function after vestibular schwannoma surgery

• Published in: Neurology India 2014-03, Vol.62 (2), p.178-182
• Main Authors: Turel, Mazda K, Babu, Krothapalli Srinivasa, Singh, Gautam, Chacko, Ari G
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Brain Neoplasms - surgery; Care and treatment; Facial nerve; Facial Nerve - physiopathology; Facial Nerve - surgery; Female; Health aspects; Humans; Male; Middle Aged; Monitoring, Intraoperative - methods; Nervous system; Nervous system tumors; Neurilemmoma - surgery; Postoperative Period; Schwann cells; Surgery; Time Factors; Treatment Outcome; Young Adult
• ISSN: 0028-3886; 1998-4022
• DOI: 10.4103/0028-3886.132373

Despite advances in vestibular schwannoma (VS) surgery and intraoperative electrophysiological monitoring, immediate and delayed facial nerve outcomes are difficult to accurately predict consistently. To determine the utility of proximal to distal facial nerve amplitude and latency ratios in predicting the long-term postoperative facial nerve function in patients undergoing excision of VS. One hundred consecutive patients undergoing surgery for VS with intraoperative facial nerve monitoring were included. Clinical, radiological, electrophysiological, and postoperative outcome data were prospectively entered into a database. Other parameters such as brainstem distance, size of the porus acousticus, and facial nerve length were also analyzed. Of the 100 patients, 53 were women. The mean age was 42.5 ± 14.1 years (range, 14-71 years) and the average tumor size was 4.1 ± 0.8 cm (range, 2.4-6.5 cm). Total excision was done in 89% of patients. Intraoperatively, the facial nerve was anatomically preserved in 86 patients, but electrophysiological responses were obtained from the root entry zone (REZ) in only 77 patients at the end of surgery, 75% of which had good facial function at long-term follow-up. In nine patients where no responses were obtained but the facial nerve was anatomically intact, 50% had good facial function at long-term follow-up. Proximal and distal amplitude and latency ratios, size or consistency of the tumor, brainstem distance, size of the porus acousticus, and length of the facial nerve were not useful in predicting long-term functional outcome. While a positive response to facial nerve stimulation at the end of VS surgery is a good predictor of long-term postoperative function, the absence of responses in an anatomically intact nerve does not preclude good function in the long term. Proximal to-distal amplitude and latency ratios did not correlate with the final facial function.