Occupational Exposure to Aflatoxin (AFB1) in Poultry Production

Aflatoxin B 1 (AFB 1 ) has been recognized to produce cancer in human liver. In addition, epidemiological and laboratory studies demonstrated that the respiratory system was a target for AFB 1 . Exposure occurs predominantly through the food chain, but inhalation represents an additional route of ex...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Toxicology and Environmental Health, Part A Part A, 2012-11, Vol.75 (22-23), p.1330-1340
Main Authors: Viegas, Susana, Veiga, Luisa, Malta-Vacas, Joana, Sabino, Raquel, Figueredo, Paula, Almeida, Ana, Viegas, Carla, Carolino, Elisabete
Format: Article
Language:English
Subjects:
Adult
Aflatoxin B1 - administration & dosage
Aflatoxin B1 - analysis
Aflatoxin B1 - blood
Aflatoxin B1 - toxicity
Aflatoxins
Air Microbiology
Air Pollution, Indoor - adverse effects
Animal Husbandry - manpower
Animals
Aspergillus - classification
Aspergillus - isolation & purification
Aspergillus flavus
Aspergillus flavus - classification
Aspergillus flavus - isolation & purification
Carcinogens - administration & dosage
Carcinogens - analysis
Carcinogens - toxicity
Colony Count, Microbial
Environmental Monitoring
Environmental Pollution - adverse effects
Female
Fungi
Humans
Inhalation Exposure - adverse effects
Male
Middle Aged
Occupational
Occupational Exposure - adverse effects
Portugal
Poultry
Recognition
Serums
Strain
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aflatoxin B 1 (AFB 1 ) has been recognized to produce cancer in human liver. In addition, epidemiological and laboratory studies demonstrated that the respiratory system was a target for AFB 1 . Exposure occurs predominantly through the food chain, but inhalation represents an additional route of exposure. The present study aimed to examine AFB 1 exposure among poultry workers in Portugal. Blood samples were collected from a total of 31 poultry workers from six poultry farms. In addition, a control group (n = 30) was included comprised of workers who undertook administrative tasks. Measurement of AFB 1 in serum was performed by enzyme-linked immunosorbent assay (ELISA). For examining fungi contamination, air samples were collected through an impaction method. Air sampling was obtained in pavilion interior and outside the premises, since this was the place regarded as the reference location. Using molecular methods, toxicogenic strains (aflatoxin-producing) were investigated within the group of species belonging to Aspergillus flavus complex. Eighteen poultry workers (59%) had detectable levels of AFB 1 with values ranging from
ISSN:1528-7394
1087-2620
2381-3504
DOI:10.1080/15287394.2012.721164