Intranasal curcumin attenuates airway remodeling in murine model of chronic asthma

Curcumin, phytochemical present in turmeric, rhizome of Curcuma longa, a known anti-inflammatory molecule with variety of pharmacological activities is found effective in murine model of chronic asthma characterized by structural alterations and airway remodeling. Here, we have investigated the effe...

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Bibliographic Details
Published in:International immunopharmacology 2014-07, Vol.21 (1), p.63-75
Main Authors: Chauhan, Preeti S., Subhashini, Dash, D., Singh, Rashmi
Format: Article
Language:English
Subjects:
Administration, Intranasal
Airway remodeling
Animals
Antibody Formation - drug effects
Asthma - chemically induced
Asthma - drug therapy
Chronic asthma
Chronic Disease
Curcuma - immunology
Curcuma longa
Curcumin - administration & dosage
Disease Models, Animal
Goblet cell
Humans
Immunoglobulin E - blood
Inflammation
Interleukin-4 - metabolism
Interleukin-5 - metabolism
Lung - drug effects
Lung - immunology
Mice
Mice, Inbred BALB C
Myocytes, Smooth Muscle - drug effects
Myocytes, Smooth Muscle - pathology
Ovalbumin - immunology
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