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Multiscale Modeling of Weakly Compressible Elastic Materials in the Harmonic Regime and Applications to Microscale Structure Estimation

This paper is devoted to the modeling of elastic materials composed of an incompressible elastic matrix and small compressible gaseous inclusions, under a time harmonic excitation. In a biomedical context, this model describes the dynamics of a biological tissue (e.g., lung) when wave analysis metho...

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Bibliographic Details
Published in:Multiscale modeling & simulation 2014-01, Vol.12 (2), p.514-537
Main Authors: Caiazzo, Alfonso, Mura, Joaquin
Format: Article
Language:English
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Summary:This paper is devoted to the modeling of elastic materials composed of an incompressible elastic matrix and small compressible gaseous inclusions, under a time harmonic excitation. In a biomedical context, this model describes the dynamics of a biological tissue (e.g., lung) when wave analysis methods (such as magnetic resonance elastography) are used to estimate tissue properties. Due to the multiscale nature of the problem, direct numerical simulations are prohibitive. We extend the homogenized model introduced in [L. Baffico et al., Multiscale Model. Simul., 7 (2008), pp. 432--465] to a time harmonic regime to describe the solid-gas mixture from a macroscopic point of view in terms of an effective elasticity tensor. Furthermore, we derive and validate numerically analytical approximations for the effective elastic coefficients in terms of macroscopic parameters. This simplified description is used to to set up an efficient variational approach for the estimation of the tissue porosity, using the mechanical response to external harmonic excitations. [PUBLICATION ABSTRACT]
ISSN:1540-3459
1540-3467
DOI:10.1137/130921866