Renal Transplantations in African Americans: A Single-center Experience of Outcomes and Innovations to Improve Access and Results

Objective To report a single-center 10-year experience of outcomes of kidney transplantation in African Americans (AAs) vs Caucasian Americans (CA) and to propose ways in which to improve kidney transplant outcomes in AAs, increased access to kidney transplantation, prevention of kidney disease, and...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2014-07, Vol.84 (1), p.68-77
Main Authors: Modlin, Charles S, Alster, Joan M, Saad, Ismail R, Tiong, Ho Yee, Mastroianni, Barbara, Savas, Kathy M, Zaramo, Carlumandarlo E.B, Kerr, Hannah L, Goldfarb, David, Flechner, Stuart M
Format: Article
Language:English
Subjects:
Adolescent
Adult
African Americans
Biological and medical sciences
Child
European Continental Ancestry Group
Female
Health Services Accessibility - statistics & numerical data
Humans
Kidney Transplantation - statistics & numerical data
Male
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Retrospective Studies
Tissue and Organ Procurement - statistics & numerical data
Tissue Donors
Treatment Outcome
Urology
Young Adult
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Summary:Objective To report a single-center 10-year experience of outcomes of kidney transplantation in African Americans (AAs) vs Caucasian Americans (CA) and to propose ways in which to improve kidney transplant outcomes in AAs, increased access to kidney transplantation, prevention of kidney disease, and acceptance of organ donor registration rates in AAs. Methods We compared outcomes of deceased donor (DD) and living donor (LD) renal transplantation in AAs vs CAs in 772 recipients of first allografts at our transplant center from January 1995 to March 2004. For DD and LD transplants, no significant differences in gender, age, body mass index, or transplant panel reactive antibody (PRA) existed between AA and CA recipients. Results Primary diagnosis of hypertension was more common in AA, DD, and LD recipients. Significant differences for DD transplants included Medicaid insurance in 23% AA compared with 7.0% CA ( P  
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2013.12.068