Continued Spirometry Changes After Cessation of Exposure in Asbestos-Cement Workers

OBJECTIVE:To assess further progression of spirometry parameters among former asbestos-cement plant workers. METHODS:The following parameters were assessedforced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and the ratio (FEV1/FVC) using a linear regression model with mixed eff...

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Published in:Journal of occupational and environmental medicine 2014-04, Vol.56 (4), p.403-408
Main Authors: Świątkowska, Beata, Wojciech, Sobala, Szubert, Zuzanna, Szeszenia-Dąbrowska, Neonila
Format: Article
Language:English
Subjects:
Adult
Aged
Asbestos
Asbestos - toxicity
Biological and medical sciences
Cement industry
Disease Progression
Female
Human exposure
Humans
Lung Diseases - diagnosis
Lung Diseases - epidemiology
Male
Medical sciences
Medical tests
Middle Aged
Occupational Diseases - diagnosis
Occupational Diseases - epidemiology
Occupational Exposure - adverse effects
Occupational health
Occupational medicine
Original Article
Poland - epidemiology
Public health. Hygiene-occupational medicine
Spirometry
Workers
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Summary:OBJECTIVE:To assess further progression of spirometry parameters among former asbestos-cement plant workers. METHODS:The following parameters were assessedforced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and the ratio (FEV1/FVC) using a linear regression model with mixed effects. RESULTS:The analysis included 3005 individuals. Spirometrically defined restrictive ventilatory defects were registered in 21.6% of the patients, obstructive defects in 8.3%, whereas mixed changes in 7%. Current smokers had significantly lower levels of FEV1, FVC, and FEV1/FVC and a steeper decline compared with nonsmokers. More rapid progression was also observed along with increasing termination of exposure. Having higher exposure was associated with a slower decline in FEV1 and FEV1/FVC ratios. CONCLUSIONS:This report indicates that asbestos-cement workers with higher cumulative exposure still had lower mean levels of spirometric parameters, despite cessation of asbestos exposure many years ago.
ISSN:1076-2752
1536-5948
DOI:10.1097/JOM.0000000000000117