Genomic Analysis of Reactive Astrogliosis

Reactive astrogliosis is characterized by a profound change in astrocyte phenotype in response to all CNS injuries and diseases. To better understand the reactive astrocyte state, we used Affymetrix GeneChip arrays to profile gene expression in populations of reactive astrocytes isolated at various...

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Bibliographic Details
Published in:The Journal of neuroscience 2012-05, Vol.32 (18), p.6391-6410
Main Authors: Zamanian, Jennifer L., Xu, Lijun, Foo, Lynette C., Nouri, Navid, Zhou, Lu, Giffard, Rona G., Barres, Ben A.
Format: Article
Language:English
Subjects:
Animals
Astrocytes - metabolism
Brain - metabolism
Brain Injuries - metabolism
Disease Models, Animal
Gene Expression Profiling - methods
Genome - genetics
Gliosis - genetics
Mice
Nerve Tissue Proteins - genetics
Nerve Tissue Proteins - metabolism
Proteome - genetics
Proteome - metabolism
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