Long-term seizure outcome after stereotactic amygdalohippocampectomy

Background The aim of the study was to evaluate the long-term seizure outcome and complications after stereotactic radiofrequency amygdalohippocampectomy (SAHE) performed for mesial temporal lobe epilepsy (MTLE). Methods The article describes the cases of 61 patients who were treated at our institut...

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Bibliographic Details
Published in:Acta neurochirurgica 2014-08, Vol.156 (8), p.1529-1537
Main Authors: Vojtěch, Zdeněk, Malíková, Hana, Krámská, Lenka, Anýž, Jiří, Syrůček, Martin, Zámečník, Josef, Liščák, Roman, Vladyka, Vilibald
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Amygdala - surgery
Clinical Article - Functional
Epilepsy, Temporal Lobe - surgery
Female
Hippocampus - surgery
Humans
Imaging, Three-Dimensional
Interventional Radiology
Intracranial Hemorrhages - etiology
Male
Medicine
Medicine & Public Health
Middle Aged
Minimally Invasive Surgery
Neurology
Neuroradiology
Neurosurgery
Neurosurgical Procedures - adverse effects
Postoperative Period
Retrospective Studies
Seizures - surgery
Surgical Orthopedics
Treatment Outcome
Young Adult
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Summary:Background The aim of the study was to evaluate the long-term seizure outcome and complications after stereotactic radiofrequency amygdalohippocampectomy (SAHE) performed for mesial temporal lobe epilepsy (MTLE). Methods The article describes the cases of 61 patients who were treated at our institution during the period 2004–2010. Mean post-operative follow-up was 5.3 years. Results At the last postsurgical visit, 43 (70.5 %) patients were Engel Class I, six (9.8 %) Class II, nine (14.8 %) Class III and three (4.9 %) Class IV. The surgery was complicated by four intracranial haematomas. One of them caused acute hydrocephalus and was treated by shunting and resolved without sequelae. After SAHE, we performed open epilepsy surgery and re-thermo lesions in three and two patients, respectively (8.2 %). There were two cases of meningitis which required antibiotic treatment. In six patients psychiatric disorders developed and one of these committed suicide due to postoperative depression. Conclusions Our results provide preliminary evidence for good long-term seizure outcomes after SAHE. SAHE could be an alternative therapy for MTLE.
ISSN:0001-6268
0942-0940
DOI:10.1007/s00701-014-2126-5