Uptake of yeast cells in the Atlantic salmon (Salmo salar L.) intestine

The intestinal mucosa is an important port of entry for many pathogens. Information of antigen uptake mechanisms is essential to understand and to possibly prevent infections. In teleosts, several studies have aimed at investigating particulate uptake in the gastrointestinal system that seems to var...

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Bibliographic Details
Published in:Developmental and comparative immunology 2014-11, Vol.47 (1), p.77-80
Main Authors: Løkka, Guro, Falk, Knut, Austbø, Lars, Koppang, Erling Olaf
Format: Article
Language:English
Subjects:
Animals
Antigen-Presenting Cells - immunology
Antigen-Presenting Cells - metabolism
Antigens, Fungal - immunology
Biological Transport
Intestines - cytology
Intestines - immunology
Intestines - microbiology
Macrophages - immunology
Saccharomyces cerevisiae
Salmo salar - immunology
Salmo salar - microbiology
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Summary:The intestinal mucosa is an important port of entry for many pathogens. Information of antigen uptake mechanisms is essential to understand and to possibly prevent infections. In teleosts, several studies have aimed at investigating particulate uptake in the gastrointestinal system that seems to vary dependent on fish species and antigen. In the present study, particulate uptake in the Atlantic salmon intestine by anal intubation of yeast cells has been investigated. In the anal intubated fish, yeast were found in the epithelium close to nuclei of macrophage-like cells and inside large mononuclear cells in the intestinal lumen, indicating uptake and possible transport of large antigen particles over the epithelium by macrophage-like cells.
ISSN:0145-305X
1879-0089
DOI:10.1016/j.dci.2014.07.005