Comparison of computer tomographic volumetry versus nuclear split renal function to determine residual renal function after living kidney donation

• Published in: Acta radiologica (1987) 2014-07, Vol.55 (6), p.753-760
• Main Authors: Patankar, Khalil, Low, Ronny Su-Tong, Blakeway, Darryn, Ferrari, Paolo
• Format: Article
• Language: English
• Subjects: Cohort Studies; Cone-Beam Computed Tomography - methods; Contrast Media; Female; Follow-Up Studies; Glomerular Filtration Rate - physiology; Humans; Iohexol; Kidney - diagnostic imaging; Kidney - physiology; Kidney Function Tests - methods; Kidney Function Tests - statistics & numerical data; Kidney Transplantation; Living Donors - statistics & numerical data; Male; Middle Aged; Pilot Projects; Radiographic Image Enhancement - methods; Radionuclide Imaging; Reproducibility of Results; Retrospective Studies; Single-Blind Method
• ISSN: 0284-1851; 1600-0455
• DOI: 10.1177/0284185113504195

Background Living-donor kidney transplantation is an established practice. Traditionally a combination of renal scintigram and computed tomography (CT) is used to select the kidney that is to be harvested in each donor. Purpose To evaluate the ability of split renal volume (SRV) calculated from volumetric examination of CT images compared to nuclear split renal function (nSRF) derived from gamma camera scintigram to predict donor residual single kidney function after donor nephrectomy. Material and Methods This pilot study comprised a retrospective analysis of CT images and renal scintigrams from 12 subsequent live kidney donors who had at least 12 months post-donation renal function follow-up. Results nSRF derived from the renal scintigram, expressed as the right kidney’s function in percent of the total, was 50.2 ± 3.3 (range, 44.1–54.0%) and SRV estimated following analysis of CT imaging was 49.0 ± 2.9 (range, 46.4–52.3%). Although the correlation between nSRF and SRV was moderate (R = 0.46), there was 92% agreement on the dominant kidney if a difference of