Design and development of a rheometer for biological fluids of limited availability

From studies on the dynamic characterization of human bones, it is noticed that reference data on the viscous behavior of the bone marrow are quite poor. Dependently from marrow limited availability and its opacity, we have not been able to retrieve a tool of appropriate characteristics able to meas...

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Bibliographic Details
Published in:Review of scientific instruments 2014-10, Vol.85 (10), p.105105-105105
Main Authors: Scorza, A, Battista, L, Silvestri, S, Sciuto, S A
Format: Article
Language:English
Subjects:
Bone marrow
Cylinders
Equipment Design
Fluid dynamics
Human behavior
Humans
Hydrodynamics
Models, Theoretical
Rheology - instrumentation
Rheometers
Rotation
Scientific apparatus & instruments
Stress, Mechanical
Viscosity
Viscosity measurement
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Summary:From studies on the dynamic characterization of human bones, it is noticed that reference data on the viscous behavior of the bone marrow are quite poor. Dependently from marrow limited availability and its opacity, we have not been able to retrieve a tool of appropriate characteristics able to measure bone marrow viscosity. Therefore, principal techniques for the viscosity measurement have been preliminarily examined, and a device suitable for viscosity measurements of biological fluids has been realized. In particular, a rotational rheometer has been developed: it is a coaxial cylinders system, where the fluid flows dragged by the inner cylinder. The device is an absolute rheometer, that is, particularly useful as nowadays it is not known the classification of the bone as far as it concerns its viscous behavior. In this work a preliminary evaluation of the metrological characteristics of the measurement system has been carried out and its main metrological performances have been evaluated.
ISSN:0034-6748
1089-7623
DOI:10.1063/1.4897490