ATSDR Science Panel on the Bioavailability of Mercury in Soils: Lessons Learned

On the basis of discussion and analysis during and following an ATSDR science panel on the bioavailability of mercury in soils, it is apparent that the default assumption of 100% relative bioavailability for mercury‐contaminated soils is excessively conservative. However, current knowledge does not...

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Bibliographic Details
Published in:Risk analysis 1997-10, Vol.17 (5), p.527-532
Main Authors: Canady, Richard A., Hanley, Jack E., Susten, Allan S.
Format: Article
Language:English
Subjects:
ATSDR
Bioavailability
Biological Availability
Environmental Health
Humans
mercury
Mercury - analysis
Mercury - pharmacokinetics
Mercury - toxicity
Methylmercury Compounds - analysis
Methylmercury Compounds - pharmacokinetics
Methylmercury Compounds - toxicity
Risk Assessment
Risk Factors
soil ingestion
Soil Pollutants - analysis
Soil Pollutants - pharmacokinetics
Soil Pollutants - toxicity
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Summary:On the basis of discussion and analysis during and following an ATSDR science panel on the bioavailability of mercury in soils, it is apparent that the default assumption of 100% relative bioavailability for mercury‐contaminated soils is excessively conservative. However, current knowledge does not allow the development of default assumptions or guidelines for determining relative bioavailability of mercury in soils. Until such default assumptions or guidelines can be developed, site‐specific assays of bioavailability, preferably using either animal bioassays or validated in vitro techniques, may provide the best approach for estimating soil‐mercury bioavailability.
ISSN:0272-4332
1539-6924
DOI:10.1111/j.1539-6924.1997.tb00894.x