Trends in Short- and Long-Term Survival Among Out-of-Hospital Cardiac Arrest Patients Alive at Hospital Arrival

BACKGROUND—Out-of-hospital cardiac arrest (OHCA) is associated with a poor prognosis and poses a significant burden to the healthcare system, but few studies have evaluated whether OHCA incidence and survival have changed over time. METHODS AND RESULTS—A population-based cohort study was conducted,...

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Published in:Circulation (New York, N.Y.) N.Y.), 2014-11, Vol.130 (21), p.1883-1890
Main Authors: Wong, Michael K.Y, Morrison, Laurie J, Qiu, Feng, Austin, Peter C, Cheskes, Sheldon, Dorian, Paul, Scales, Damon C, Tu, Jack V, Verbeek, P Richard, Wijeysundera, Harindra C, Ko, Dennis T
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cohort Studies
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Emergency Service, Hospital - trends
Female
Humans
Male
Medical sciences
Middle Aged
Out-of-Hospital Cardiac Arrest - diagnosis
Out-of-Hospital Cardiac Arrest - mortality
Out-of-Hospital Cardiac Arrest - therapy
Population Surveillance - methods
Survival Rate - trends
Time-to-Treatment - trends
Young Adult
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Summary:BACKGROUND—Out-of-hospital cardiac arrest (OHCA) is associated with a poor prognosis and poses a significant burden to the healthcare system, but few studies have evaluated whether OHCA incidence and survival have changed over time. METHODS AND RESULTS—A population-based cohort study was conducted, including 34 291 OHCA patients >20 years of age who were transported alive to the emergency department of an acute-care hospital from April 1, 2002, to March 31, 2012, in Ontario, Canada. Patients with life-threatening trauma and those who died before hospital arrival were excluded. The overall age- and sex-standardized incidence of OHCA patients who were transported alive was 36 cases per 100 000 persons and did not significantly change over the study period. Cardiac risk factor prevalence increased significantly, whereas the rate of most cardiovascular conditions decreased significantly. The 30-day survival improved from 9.4% in 2002 to 13.6% in 2011; 1-year survival improved from 7.7% to 11.8% (P
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.114.010633