Passive protection against Salmonella enterica serovar Enteritidis infection from maternally derived antibodies of hens vaccinated with a ghost vaccine

•The ghost vaccine can cause prenatal hens to have a normal immune response.•Chicks from vaccinated hens acquired high levels of serum against S. Enteritidis.•Maternal antibodies could confer protection against S. Enteritidis infection. This study evaluated maternal immunity against Salmonella enter...

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Bibliographic Details
Published in:Research in veterinary science 2014-10, Vol.97 (2), p.191-193
Main Authors: Si, Wei, Yu, Shenye, Chen, Liping, Wang, Xiumei, Zhang, Wanjiang, Liu, Siguo, Li, Guangxing
Format: Article
Language:English
Subjects:
Animals
Antibodies, Bacterial - immunology
Bacterial Vaccines - immunology
Chickens - immunology
Domestic fowl
Egg Yolk - microbiology
Enzyme-Linked Immunosorbent Assay
Female
Freeze Drying
Ghost vaccine
Immunity, Maternally-Acquired - immunology
Immunization, Passive - methods
Immunization, Passive - veterinary
Maternally-derived antibodies
Plasmids
Poultry Diseases - immunology
Poultry Diseases - mortality
Poultry Diseases - prevention & control
Salmonella enterica
Salmonella enterica serovar Enteritidis
Salmonella enteritidis - immunology
Salmonella Infections, Animal - immunology
Salmonella Infections, Animal - mortality
Salmonella Infections, Animal - prevention & control
Specific Pathogen-Free Organisms
Survival Rate
Vaccination - methods
Vaccination - veterinary
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Summary:•The ghost vaccine can cause prenatal hens to have a normal immune response.•Chicks from vaccinated hens acquired high levels of serum against S. Enteritidis.•Maternal antibodies could confer protection against S. Enteritidis infection. This study evaluated maternal immunity against Salmonella enterica serovar Enteritidis acquired through the egg yolk. Two-hundred 19-week-old specific pathogen free (SPF) broiler breeders which were randomly divided into two groups of equal size were injected with S. Enteritidis ghosts (5 × 109 colony forming units in 0.1 ml per hen) and phosphate-buffered saline (PBS, 0.01 mol⋅l−1, pH 7.4) twice, respectively, with an interval of 2 weeks. An indirect enzyme-linked immunosorbent assay (ELISA) was applied to detect specific antibodies against S. Enteritidis. S. Enteritidis-specific antibody levels in the vaccinated group increased over time and were significantly higher than those of the control group on days 28 (P 
ISSN:0034-5288
1532-2661
DOI:10.1016/j.rvsc.2014.08.001