Childhood vaccines and Kawasaki disease, Vaccine Safety Datalink, 1996-2006

Highlights • Longitudinal, multi-site study on 1.7 million children for 4.4 million person-years. • No evidence for increased rate of Kawasaki disease following vaccination. • Observed decreased rate of Kawasaki disease during 42 days after vaccination. • Findings provide strong evidence that vaccin...

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Bibliographic Details
Published in:Vaccine 2015-01, Vol.33 (2), p.382-387
Main Authors: Abrams, Joseph Y, Weintraub, Eric S, Baggs, James M, McCarthy, Natalie L, Schonberger, Lawrence B, Lee, Grace M, Klein, Nicola P, Belongia, Edward A, Jackson, Michael L, Naleway, Allison L, Nordin, James D, Hambidge, Simon J, Belay, Ermias D
Format: Article
Language:English
Subjects:
Adverse Drug Reaction Reporting Systems
Adverse events
Allergy and Immunology
Child
Child, Preschool
Etiology
Female
Health risk assessment
Humans
Immunization
Infant
Infant, Newborn
Kawasaki disease
Longitudinal Studies
Male
Medical records
Mucocutaneous Lymph Node Syndrome - epidemiology
Mucocutaneous Lymph Node Syndrome - etiology
Regression Analysis
Risk Factors
Time Factors
United States - epidemiology
Vaccination
Vaccine Safety Datalink
Vaccines
Vaccines - adverse effects
Vasculitis
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Summary:Highlights • Longitudinal, multi-site study on 1.7 million children for 4.4 million person-years. • No evidence for increased rate of Kawasaki disease following vaccination. • Observed decreased rate of Kawasaki disease during 42 days after vaccination. • Findings provide strong evidence that vaccines are not a cause of Kawasaki disease.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2014.10.044