HCH and DDT in surface extractable skin lipid as a measure of human exposure in India

DDT and hexachlorocyclohexane (HCH) content of skin lipids and blood were determined in 39 subjects living in the Mathura district of India, 15 of whom had occupational exposure to the pesticides in malaria control spraying operations. Skin lipids were obtained by swabbing the face with ethanol soak...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 1998-02, Vol.60 (2), p.238-244
Main Authors: Dua, V.K, Pant, C.S, Sharma, V.P, Pathak, G.K
Format: Article
Language:English
Subjects:
Biological and medical sciences
Body Burden
Chemical compounds (mineral, organic)
Chemical, physic and infectious diseases
DDT
DDT - analysis
DDT - blood
Environmental Monitoring
Face
HCH
Hexachlorocyclohexane
Hexachlorocyclohexane - analysis
Hexachlorocyclohexane - blood
Humans
INDE
INDIA
Insecticides - analysis
Insecticides - blood
LIPIDE
LIPIDOS
LIPIDS
Medical sciences
Occupational Exposure - analysis
Occupational medicine
PEAU
PIEL (ANIMAL)
Public health. Hygiene-occupational medicine
SKIN
Skin - chemistry
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Summary:DDT and hexachlorocyclohexane (HCH) content of skin lipids and blood were determined in 39 subjects living in the Mathura district of India, 15 of whom had occupational exposure to the pesticides in malaria control spraying operations. Skin lipids were obtained by swabbing the face with ethanol soaked defatted cotton wool two hours after the face had been washed with soap. Blood samples from those having occupational exposure to the pesticides contained 1.3 to 1.4 times as much pesticide as blood samples from the general population. For this population a correlation between skin lipid and blood concentrations of gamma - and beta -HCH, total HCH, total DDT, DDE and DDT residues was obtained. For those having occupational exposure, correlations were found only for DDE, total HCH, and beta -HCH. The insignificant correlation for DDT and gamma -HCH of the occupationally exposed group could be due to recent exposure to the compounds during spraying. Therefore, the use of skin lipid concentrations of these pesticides as a biological indicator of exposure may be useful only for studies of the general population, due to dermal exposure of the occupationally exposed groups.
ISSN:0007-4861
1432-0800
DOI:10.1007/s001289900616