Severe Anemia, Gastric Ulcer, Pneumonitis and Cholangitis in a Liver Transplant Patient: Multiple Organic Dysfunction and One Etiology: A Case Report

Abstract Cytomegalovirus (CMV) is the most common viral pathogen that negatively affects the outcome of liver transplantation. CMV causes febrile illness often accompanied by bone marrow suppression, and in some cases it invades tissues, including the transplanted allograft. In addition, CMV has bee...

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Bibliographic Details
Published in:Transplantation proceedings 2015, Vol.47 (1), p.136-138
Main Authors: García-Pajares, F, Santos-Santamarta, F, Fernández-Fontecha, E, Sánchez-Ocaña, R, Amo-Alonso, R, Loza-Vargas, A, Madrigal, B, Pérez-Saborido, B, Almohalla, C, Sánchez-Antolín, G
Format: Article
Language:English
Subjects:
Anemia - complications
Cholangitis - complications
Cytomegalovirus Infections - complications
Graft Rejection - etiology
Humans
Liver Transplantation - adverse effects
Male
Middle Aged
Opportunistic Infections - complications
Pneumonia - complications
Stomach Ulcer - complications
Surgery
Transplantation, Homologous - adverse effects
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Summary:Abstract Cytomegalovirus (CMV) is the most common viral pathogen that negatively affects the outcome of liver transplantation. CMV causes febrile illness often accompanied by bone marrow suppression, and in some cases it invades tissues, including the transplanted allograft. In addition, CMV has been significantly associated with an increased predisposition to allograft rejection, accelerated hepatitis C recurrence, and other opportunistic infections, as well as reduced overall patient and allograft survivals. We carried out a study on a Spanish adult liver transplant recipient who rapidly presented anemia and was diagnosed as having Coomb negative (nonimmune) hemolytic anemia, gastric ulcer, pneumonitis, and cholangitis associated with a CMV infection.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2014.11.019