Integration of genomic and proteomic analyses in the classification of the Siphoviridae family

Abstract Using a variety of genomic (BLASTN, ClustalW) and proteomic (Phage Proteomic Tree, CoreGenes) tools we have tackled the taxonomic status of members of the largest bacteriophage family, the Siphoviridae . In all over 400 phages were examined and we were able to propose 39 new genera, compris...

Full description

Saved in:
Bibliographic Details
Published in:Virology (New York, N.Y.) N.Y.), 2015-03, Vol.477, p.144-154
Main Authors: Adriaenssens, Evelien M, Edwards, Rob, Nash, John H.E, Mahadevan, Padmanabhan, Seto, Donald, Ackermann, Hans-Wolfgang, Lavigne, Rob, Kropinski, Andrew M
Format: Article
Language:English
Subjects:
Bacteriophages - chemistry
Bacteriophages - classification
Bacteriophages - genetics
ClustalW
CoreGenes
Genome, Viral
Genomics - methods
ICTV
Infectious Disease
Phage Proteomic Tree
Proteome - analysis
Proteomics - methods
Siphoviridae
Siphoviridae - chemistry
Siphoviridae - classification
Siphoviridae - genetics
Taxonomy
Viral Proteins - analysis
Virology - methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Using a variety of genomic (BLASTN, ClustalW) and proteomic (Phage Proteomic Tree, CoreGenes) tools we have tackled the taxonomic status of members of the largest bacteriophage family, the Siphoviridae . In all over 400 phages were examined and we were able to propose 39 new genera, comprising 216 phage species, and add 62 species to two previously defined genera ( Phic3unalikevirus; L5likevirus ) grouping, in total, 390 fully sequenced phage isolates. Many of the remainders are orphans which the Bacterial and Archaeal Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) chooses not to ascribe genus status at the time being.
ISSN:0042-6822
1096-0341
DOI:10.1016/j.virol.2014.10.016