Febrile seizures following measles and varicella vaccines in young children in Australia

Abstract Background Febrile seizures (FS) are common in childhood with incidence peaking in the second year of life when measles and varicella-containing vaccines are administered. This study aimed to examine the vaccine-attributable risk of FS following separate administration of MMR and monovalent...

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Bibliographic Details
Published in:Vaccine 2015-03, Vol.33 (11), p.1412-1417
Main Authors: Macartney, Kristine K, Gidding, Heather F, Trinh, Lieu, Wang, Han, McRae, Jocelynne, Crawford, Nigel, Gold, Michael, Kynaston, Anne, Blyth, Christopher, Yvonne, Zurynski, Elliott, Elizabeth, Booy, Robert, Buttery, Jim, Marshall, Helen, Nissen, Michael, Richmond, Peter, McInytre, Peter B, Wood, Nicholas
Format: Article
Language:English
Subjects:
Age
Allergy and Immunology
Australia - epidemiology
Chickenpox Vaccine - adverse effects
Child
Child, Preschool
Children & youth
Epidemiology
Febrile seizures
Female
Hospitals
Humans
Immunization
Incidence
Infant
Male
Measles
Measles-Mumps-Rubella Vaccine - adverse effects
Measles–mumps–rubella vaccine
Mumps
Risk
Risk assessment
Risk Factors
Seizures, Febrile - epidemiology
Seizures, Febrile - etiology
Studies
Vaccine safety
Vaccines
Vaccines, Combined
Varicella vaccine
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Summary:Abstract Background Febrile seizures (FS) are common in childhood with incidence peaking in the second year of life when measles and varicella-containing vaccines are administered. This study aimed to examine the vaccine-attributable risk of FS following separate administration of MMR and monovalent varicella vaccines (VV) prior to a planned change to MMRV as the second dose of measles-containing vaccine at 18 months of age. Methods All FS cases in children aged
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2014.10.071