Alcohol Use Disorders in patients with schizophrenia: Comparative study with general population controls

Abstract Objective To compare the prevalence of Alcohol Use Disorders (AUD) among schizophrenia patients with that of the general population in a south Indian rural community. Methods Alcohol use pattern of 254 schizophrenia patients in the past year was compared with randomly selected healthy compa...

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Published in:Addictive behaviors 2015-06, Vol.45, p.22-25
Main Authors: Kumar, Channaveerachari Naveen, Thirthalli, Jagadisha, Suresha, Kudumallige Krishnappa, Arunachala, Udupi, Gangadhar, Bangalore N
Format: Article
Language:English
Subjects:
Adult
Alcohol use
Alcohol Use Disorders
Alcohol-Related Disorders - epidemiology
Alcoholism - epidemiology
Case-Control Studies
Comorbidity
Comparative analysis
Educational Status
Female
Humans
India - epidemiology
Logistic Models
Male
Middle Aged
Patients
Prevalence
Psychiatry
Regression analysis
Residence Characteristics
Risk Factors
Rural areas
Rural India
Rural Population - statistics & numerical data
Schizophrenia
Schizophrenia - epidemiology
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Summary:Abstract Objective To compare the prevalence of Alcohol Use Disorders (AUD) among schizophrenia patients with that of the general population in a south Indian rural community. Methods Alcohol use pattern of 254 schizophrenia patients in the past year was compared with randomly selected healthy comparison subjects (n = 350) from the same community in an administrative block of rural India using the Alcohol Use Disorders Identification Test (AUDIT). Results A significantly smaller proportion of patients used alcohol in the past year (10.2%; 95% CI: 6.5%–14.0%) than controls (18.3%; 95% CI: 15.8%–24.1%; OR = 2.2; 95% CI = 1.4–3.5). This was true for AUD (hazardous use and harmful use; total AUDIT score > 8) also: 5.5% patients (95% CI: 2.7%–8.3%) and 10.3% controls (95% CI: 7.1%–13.4%) had hazardous use (OR = 2.0; 95% CI = 1.0–3.7). Hazardous use was associated with domicile in villages and lesser years of education. On logistic regression, after controlling for these confounds, the odds of having AUD were 2.7 times more for controls than for patients (95% CI = 1.4–5.2). Conclusions Prevalence of AUD is significantly lower in patients than in the general population in this community. Cross-cultural studies are needed to elucidate factors that underlie contrasting results across different countries.
ISSN:0306-4603
1873-6327
DOI:10.1016/j.addbeh.2015.01.009