Modeling of dipole-dipole-coupled, electric field-driven, protein-based computing architectures

• Published in: International journal of circuit theory and applications 2015-01, Vol.43 (1), p.60-72
• Main Author: Rakos, Balázs
• Format: Article
• Language: English
• Subjects: Circuits; Computation; Computer programs; Computer simulation; computing architectures; Coulomb coupling; Coupling (molecular); digital signal processing; Mathematical models; molecular electronics; nanoelectronics; protein; Proteins; Switching
• ISSN: 0098-9886; 1097-007X
• DOI: 10.1002/cta.1924

In the present study, we propose a novel approach for the realization of protein‐based logic circuits potentially suitable for nanoscale digital signal processing and computing architectures. Electric field‐induced switching of Dronpa, an artificial protein, is demonstrated through simulations with the NAMD molecular dynamics simulation software, and a circuit model that describes such switching behavior is presented. Simulations suggest that digital signal propagation and the majority gate can be realized by the utilization of such proteins if they are dipole–dipole coupled and are driven by proper electric fields. Copyright © 2013 John Wiley & Sons, Ltd. We propose a novel approach for the realization of protein‐based logic circuits potentially suitable for nanoscale digital signal processing and computing. Electric field‐induced switching of Dronpa, an artificial protein, is demonstrated through simulations with the NAMD molecular dynamics simulation software, and a circuit model that describes such switching behavior is presented. Simulations suggest that digital signal propagation and the majority gate can be realized with such proteins if they are dipole–dipole coupled and are driven by proper electric fields.