Volumetric femoral BMD, bone geometry, and serum sclerostin levels differ between type 2 diabetic postmenopausal women with and without fragility fractures

Summary While type 2 diabetes (T2D) is associated with higher skeletal fragility, specific risk stratification remains incompletely understood. We found volumetric bone mineral density, geometry, and serum sclerostin differences between low-fracture risk and high-fracture risk T2D women. These featu...

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Bibliographic Details
Published in:Osteoporosis international 2015-04, Vol.26 (4), p.1283-1293
Main Authors: Heilmeier, U., Carpenter, D. R., Patsch, J. M., Harnish, R., Joseph, G. B., Burghardt, A. J., Baum, T., Schwartz, A. V., Lang, T. F., Link, T. M.
Format: Article
Language:English
Subjects:
Adaptor Proteins, Signal Transducing
Aged
Anthropometry - methods
Biomarkers - blood
Bone density
Bone Density - physiology
Bone Morphogenetic Proteins - blood
Case-Control Studies
Diabetes
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - physiopathology
Endocrinology
Female
Femur - diagnostic imaging
Femur - physiopathology
Femur Neck - diagnostic imaging
Femur Neck - physiopathology
Fractures
Genetic Markers
Glycoproteins
Humans
Medicine
Medicine & Public Health
Menopause
Middle Aged
Original
Orthopedics
Osteoporotic Fractures - blood
Osteoporotic Fractures - diagnostic imaging
Osteoporotic Fractures - etiology
Osteoporotic Fractures - physiopathology
Rheumatology
Risk Assessment - methods
Risk factors
Tomography
Tomography, X-Ray Computed - methods
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