HIV-associated salivary gland disease - clinical or imaging diagnosis?

Objectives This work aimed at studying the salivary gland disease (SGD) as it relates to associated factors, such as persistent generalised lymphadenopathy (PGL), lymphocytic interstitial pneumonia (LIP), clinical and immunological features of AIDS, and salivary flow rate and pH, as well as at explo...

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Published in:International journal of paediatric dentistry 2015-07, Vol.25 (4), p.233-238
Main Authors: da Silva Rath, Inês Beatriz, Beltrame, Ana Paula C. A., Carvalho, Aroldo P., Schaeffer, Marcela B., Almeida, Izabel C. S.
Format: Article
Language:English
Subjects:
Brazil - epidemiology
Child
Child, Preschool
Cross-Sectional Studies
Dentistry
Female
HIV
HIV Infections - complications
HIV Infections - epidemiology
Human immunodeficiency virus
Humans
Hydrogen-Ion Concentration
Incidence
Lung Diseases, Interstitial - virology
Lymphadenopathy - virology
Male
Pediatrics
Prevalence
Saliva - virology
Salivary Gland Diseases - diagnostic imaging
Salivary Gland Diseases - epidemiology
Salivary Gland Diseases - virology
Salivation
Ultrasonography - methods
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Summary:Objectives This work aimed at studying the salivary gland disease (SGD) as it relates to associated factors, such as persistent generalised lymphadenopathy (PGL), lymphocytic interstitial pneumonia (LIP), clinical and immunological features of AIDS, and salivary flow rate and pH, as well as at exploring the relationship between the clinical diagnosis and the imaging diagnosis by ultrasound (US) examination of the parotid glands. Methods Information regarding the observation of parotid gland enlargement, PGL, LIP, and clinical and immunological features of AIDS was gathered from medical records, and a saliva sample for unstimulated salivary flow rate and pH measurement was collected from 142 children aged 3 through 10 years treated at the Department of Infectious Diseases of Joana de Gusmão Children's Hospital, Florianópolis, SC, Brazil. High‐resolution ultrasonography was performed in 58 children. Pearson's chi‐square test and t‐test were used to evaluate the association between the variables. Results A significant association was found between SGD and LIP. Ultrasound revealed a 50% higher incidence of SGD that was not reported in the patients' records. Conclusion US examination proved to be essential for the correct diagnosis and monitoring of the progression of HIV/SGD.
ISSN:0960-7439
1365-263X
DOI:10.1111/ipd.12133