Patient reported outcomes of the ­clinical use of a proprietary topical dry mouth product

ABSTRACT Purpose To present patient reported changes in oral symptoms in response to an open‐label product trial conducted in patients self‐identifying as having Sjögren's syndrome. Methods A survey was conducted in conjunction with the Sjögren's Syndrome Foundation and 151 foundation memb...

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Bibliographic Details
Published in:Special care in dentistry 2015-07, Vol.35 (4), p.197-204
Main Authors: Epstein, Joel B., Villines, Dana C., Sroussi, Herve Y.
Format: Article
Language:English
Subjects:
Administration, Topical
Aged
Clinical outcomes
Dentistry
Dimethylpolysiloxanes - administration & dosage
Drug Combinations
dysguesia
Emulsions
Female
Health & beauty aids
Humans
Male
mouth and throat pain
Oral hygiene
Patient Reported Outcome Measures
Poloxamer - administration & dosage
quality of life
salivation
Sjogren's Syndrome - drug therapy
Sjögren's syndrome
Treatment Outcome
United States
xerostomia
Xerostomia - drug therapy
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Summary:ABSTRACT Purpose To present patient reported changes in oral symptoms in response to an open‐label product trial conducted in patients self‐identifying as having Sjögren's syndrome. Methods A survey was conducted in conjunction with the Sjögren's Syndrome Foundation and 151 foundation members completed a survey rating their common oral symptoms, based upon the Vanderbilt Head and Neck Symptom Survey before and after use of the trial products, including rinse, ­lozenges, gel, and spray. Results Subjects reported multiple oral symptoms with the highest rated symptoms involving dry mouth with 80% of symptoms showing statistically significant reduction from pre‐ to posttest. The largest symptom reductions were in dry mouth symptoms and dietary problems. Conclusions Symptoms of dry mouth were improved with use of MedActive® products. Increased ease of taking oral medications also was reported. Improvement in mouth/throat pain was noted. Subjects reported considerable effect of the test product upon dry mouth and oral symptoms.
ISSN:0275-1879
1754-4505
DOI:10.1111/scd.12112