Office-Based Balloon Sinus Dilation: 1-Year Follow-up of a Prospective, Multicenter Study

• Published in: Annals of otology, rhinology & laryngology rhinology & laryngology, 2015-08, Vol.124 (8), p.630-637
• Main Authors: Sikand, Ashley, Silvers, Stacey L., Pasha, Raza, Shikani, Alan, Karanfilov, Boris I., Harfe, Dan T., Sillers, Michael J.
• Format: Article
• Language: English
• Subjects: Ambulatory Surgical Procedures; Chronic Disease; Dilatation - adverse effects; Dilatation - methods; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nasal Surgical Procedures - adverse effects; Nasal Surgical Procedures - methods; Natural Orifice Endoscopic Surgery - adverse effects; Natural Orifice Endoscopic Surgery - methods; Paranasal Sinuses - surgery; Postoperative Complications - diagnostic imaging; Postoperative Complications - psychology; Postoperative Period; Quality of Life; Recurrence; Rhinitis - diagnosis; Rhinitis - physiopathology; Rhinitis - psychology; Rhinitis - surgery; Sinusitis - diagnosis; Sinusitis - physiopathology; Sinusitis - psychology; Sinusitis - surgery; Tomography, X-Ray Computed; Treatment Outcome
• ISSN: 0003-4894; 1943-572X
• DOI: 10.1177/0003489415573830

Objective: Balloon sinus dilation (BSD) instruments afford the opportunity for office-based sinus procedures in properly selected patients with chronic rhinosinusitis (CRS). This study evaluated patient-reported outcomes 1 year after office-based BSD. Methods: Adult patients with medically refractory CRS were prospectively enrolled into a multicenter, single-arm study and treated with office-based BSD under local anesthesia. Follow-up on 203 patients was conducted at 2, 8, and 24 weeks postsurgery using validated outcome measures for quality of life (SNOT-20) and computed tomography imaging (Lund-Mackay score). After 24 weeks, patients were re-enrolled for 1-year follow-up to evaluate changes in SNOT-20 scores and revisions. Results: All patients who re-enrolled (n = 122) completed the study, with an average follow-up of 1.4 years. Neither preoperative SNOT-20 nor Lund-Mackay CT scores were predictive of re-enrollment and return for follow-up. Compared to baseline, improvements in SNOT-20 scores remained statistically significant (P < .001) and clinically meaningful (mean decrease ≥ 0.8). In patients followed to 1.4 years, 9 of 122 (7.4%) had revision surgery. Conclusion: Following office-based BSD, significant improvements in quality of life observed at 24 weeks were maintained 1 year postsurgery. These extended results provide further evidence of office-based BSD as an effective, minimally invasive procedure for appropriately selected patients with CRS.