A "Renaissance" in Radical Trifluoromethylation

This Minireview highlights recent developments in radical trifluoromethylation reactions. The trifluoromethyl group belongs to the privileged moieties in medicinal chemistry. Many drugs and drug candidates contain a trifluoromethyl substituent. Also in agrochemicals, the CF3 moiety often appears. Th...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2012-09, Vol.51 (36), p.8950-8958
Main Author: Studer, Armido
Format: Article
Language:English
Subjects:
Agricultural chemicals
Agrochemicals
Alkenes
Alkenes - chemistry
Aromatic compounds
aromatic substitution
Catalysis
Covering
Drugs
Free Radicals - chemistry
Hydrocarbons, Fluorinated - chemistry
Methylation
Oxidation-Reduction
Pharmaceutical industry
Pharmaceutical Preparations - chemistry
radical reactions
Radicals
Ruthenium - chemistry
synthetic methods
trifluoromethylation
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