Extreme Hyperlactatemia After Heart Transplantation: One Center's Experience

Abstract Introduction Hyperlactatemia may occur early after cardiac surgery and is correlated with prognosis. This study was conducted to analyze the perioperative variables and postoperative outcomes among heart transplant recipients with extremely high lactate levels (>15 mmol/L). Methods The s...

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Published in:Transplantation proceedings 2015-07, Vol.47 (6), p.1945-1948
Main Authors: Hsu, Y.C, Hsu, C.H, Huang, G.S, Lu, C.C, Wu, Z.F, Tsai, Y.T, Lin, C.Y, Lin, Y.C, Tsai, C.S, Lin, T.C
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Language:English
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Summary:Abstract Introduction Hyperlactatemia may occur early after cardiac surgery and is correlated with prognosis. This study was conducted to analyze the perioperative variables and postoperative outcomes among heart transplant recipients with extremely high lactate levels (>15 mmol/L). Methods The single-center medical records of heart transplantation from June 2006 to May 2013 were retrospectively reviewed for patient characteristics, perioperative hemodynamic variables, arterial blood gas analysis data, and postoperative mortality. Results Among 58 consecutive heart transplant recipients, lactate levels over the detectable upper limit (>15 mmol/L) were identified in 12 patients after intensive care unit admission, with peak time at 1.9 ± 2.0 (range 0–6.1) hours. The maximal preoperative lactate level was 3.1 mmol/L, and most (11/12) postoperative lactate levels returned to 
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2015.02.027