Association of IL-6, TNF-α and IL-10 gene polymorphisms with type 2 diabetes mellitus

Type 2 diabetes mellitus (T2DM) is a metabolic pro-inflammatory disorder characterized by chronic hyperglycemia and increased levels of circulating cytokines suggesting a causal role of inflammation in its etiology. Polymorphism of cytokine genes including interleukin-6 ( IL - 6 ), tumour necrosis f...

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Bibliographic Details
Published in:Molecular biology reports 2013-11, Vol.40 (11), p.6271-6279
Main Authors: Saxena, Madhukar, Srivastava, Neena, Banerjee, Monisha
Format: Article
Language:English
Subjects:
Alleles
Animal Anatomy
Animal Biochemistry
Biomedical and Life Sciences
Case-Control Studies
computer software
confidence interval
Diabetes Mellitus, Type 2 - genetics
Diabetes Mellitus, Type 2 - metabolism
DNA
etiology
Gene Frequency
Genetic Association Studies
genotyping
Haplotypes
Histology
Humans
hyperglycemia
India
inflammation
interleukin-10
Interleukin-10 - genetics
interleukin-6
Interleukin-6 - genetics
Life Sciences
Linkage Disequilibrium
Morphology
necrosis
neoplasms
noninsulin-dependent diabetes mellitus
Odds Ratio
patients
polymerase chain reaction
Polymorphism, Genetic
Polymorphism, Single Nucleotide
regression analysis
restriction fragment length polymorphism
risk
tumor necrosis factor-alpha
Tumor Necrosis Factor-alpha - genetics
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