Nausea, vomiting and quality of life of patients with cancer undergoing antineoplastic treatment: an evaluation by pharmacists

Objective This study aims to evaluate the frequency and severity of nausea and vomiting using two different instruments and relate them to quality of life (QOL) in patients with cancer receiving antineoplastic treatment. Methods Severity of chemotherapy‐induced nausea and vomiting (CINV) was measure...

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Bibliographic Details
Published in:The International journal of pharmacy practice 2015-10, Vol.23 (5), p.357-360
Main Authors: de Souza, Cinthia Madeira, Visacri, Marília Berlofa, Ferrari, Graziele Baldan, Tuan, Bruna Taliani, Costa, Anna Paula Lourenço, Barbosa, Cristina Rosa, Lima, Carmen Silvia P., Mazzola, Priscila Gava, Moriel, Patrícia
Format: Article
Language:English
Subjects:
Antineoplastic Agents - adverse effects
antineoplastic treatment
Brazil - epidemiology
Cancer
Cancer therapies
Female
Humans
Male
Middle Aged
Nausea
Nausea - chemically induced
Nausea - diagnosis
Nausea - epidemiology
Neoplasms - complications
Neoplasms - drug therapy
Pharmacists
Quality of Life
Severity of Illness Index
Vomiting
Vomiting - chemically induced
Vomiting - diagnosis
Vomiting - epidemiology
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Summary:Objective This study aims to evaluate the frequency and severity of nausea and vomiting using two different instruments and relate them to quality of life (QOL) in patients with cancer receiving antineoplastic treatment. Methods Severity of chemotherapy‐induced nausea and vomiting (CINV) was measured by Common Terminology Criteria for Adverse Events (CTCAE) and a numerical scale. QOL was assessed using the Functional Assessment of Cancer Therapy‐General questionnaire. Key findings Of the 50 patients studied, 60.0% reported nausea (40.0% CTCAE grade 1; 66.7% moderate intensity on numerical scale) and 30.0% reported vomiting (46.7% CTCAE grades 1 and 2, each; 66.7% moderate intensity on numerical scale). CINV did not influence overall QOL. Conclusion The frequency of CINV was high. There was no association between nausea/vomiting and overall QOL.
ISSN:0961-7671
2042-7174
DOI:10.1111/ijpp.12169