Osteosarcoma in patients younger than 12 years old without metastases have similar prognosis as adolescent and young adults

Background Childhood cancer is relatively rare and tends to present specific age distribution, as a prognostic factor for some of these diseases. Information on how young age affects prognosis, response to chemotherapy, and local control options in children versus AYA with osteosarcoma (OST) is mini...

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Bibliographic Details
Published in:Pediatric blood & cancer 2015-07, Vol.62 (7), p.1209-1213
Main Authors: Eleutério, Sabrina Jeane Prates, Senerchia, Andreza Almeida, Almeida, Maria Teresa, Costa, Cecilia Maria Da, Lustosa, Daniel, Calheiros, Luiz Mario, Barreto, Jose Henrique Silva, Brunetto, Algemir Lunardi, Macedo, Carla Renata Pacheco Donato, Petrilli, Antonio Sergio
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
amputation
Bone Neoplasms - mortality
Bone Neoplasms - pathology
Bone Neoplasms - surgery
chemotherapy
Child
Child, Preschool
childhood bone cancer
children
Extremities - pathology
Extremities - surgery
Female
Follow-Up Studies
Hematology
Humans
Infant
Infant, Newborn
Male
Neoplasm Recurrence, Local - mortality
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - surgery
Neoplasm Staging
Oncology
osteosarcoma
Osteosarcoma - mortality
Osteosarcoma - secondary
Osteosarcoma - surgery
Pediatrics
Prognosis
Survival Rate
Young Adult
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Summary:Background Childhood cancer is relatively rare and tends to present specific age distribution, as a prognostic factor for some of these diseases. Information on how young age affects prognosis, response to chemotherapy, and local control options in children versus AYA with osteosarcoma (OST) is minimal. Methods In order to identify the main differences in clinicalpathologic features, surgical approaches and survival rates of primary high grade OST of the extremity between children (n = 156;
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.25459