From Arabia to Iberia: A Y chromosome perspective

• Published in: Gene 2015-06, Vol.564 (2), p.141-152
• Main Authors: Regueiro, María, Garcia-Bertrand, Ralph, Fadhlaoui-Zid, Karima, Álvarez, Joseph, Herrera, Rene J.
• Format: Article
• Language: English
• Subjects: Africa, Northern; Chromosomes, Human, Y; Gene Flow; Haplotypes; Human Migration; Humans; Microsatellite Repeats; Middle East; Muslim migration of Iberia; Phylogenetic relationships; Spain; Y haplogroups E and J; Y-STR
• ISSN: 0378-1119; 1879-0038
• DOI: 10.1016/j.gene.2015.02.042

At different times during recent human evolution, northern Africa has served as a conduit for migrations from the Arabian Peninsula. Although previous researchers have investigated the possibility of the Strait of Gibraltar as a pathway of migration from North Africa to Iberia, we now revisit this issue and theorize that although the Strait of Gibraltar, at the west end of this corridor, has acted as a barrier for human dispersal into Southwest Europe, it has not provided an absolute seal to gene flow. To test this hypothesis, here we use the spatial frequency distributions, STR diversity and expansion time estimates of Y chromosome haplogroups J1-P58 and E-M81 to investigate the genetic imprints left by the Arabian and Berber expansions into the Iberian Peninsula, respectively. The data generated indicate that Arabian and Berber genetic markers are detected in Iberia. We present evidence that suggest that Iberia has received gene flow from Northwest Africa during and prior to the Islamic colonization of 711A.D. It is interesting that the highest frequencies of Arabia and Berber markers are not found in southern Spain, where Islam remained the longest and was culturally most influential, but in Northwest Iberia, specifically Galicia. We propose that Moriscos' relocations to the north during the Reconquista, the migration of cryptic Muslims seeking refuge in a more lenient society and/or more geographic extensive pre-Islamic incursions may explain the higher frequencies and older time estimates of mutations in the north of the Peninsula. These scenarios are congruent with the higher diversities of some diagnostic makers observed in Northwest Iberia. •The M81 and M183 mutations in Spain represent signatures of Berber gene flow.•The P58 mutation and its derivatives represent genetic signals from Arabia.•Our data are compatible with multiple migrations from Northwest Africa including the Islamic occupation.•Frequencies of both Arabic and Berber markers are higher at the extreme Northwest of Iberian compared to the South of Spain.•Exodus of converts and pre-Islamic dispersals to North Iberia may explain the higher frequencies compared to South Iberia.