Selective colorimetric assay of cyanide ions using a thioamide-based probe containing phenol and pyridyl groups

[Display omitted] The selective assay of cyanide ions with a thioamide compound (HNPTU) containing phenol and pyridine as a chemosensor is reported using absorbance changes in a buffered aqueous solution (50mM HEPES, pH 7.4) containing ethanol. Upon treatment with cyanide ions, the colorless solutio...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2014-12, Vol.55 (51), p.6965-6968
Main Authors: Song, Eun Joo, Kim, Soojin, Park, Gyeong Jin, Park, Sol Ji, Choi, Ye Won, Kim, Cheal, Kim, Jinheung
Format: Article
Language:English
Subjects:
Absorbance
Anions
Assaying
Colorimetric sensor
Colorimetry
Cyanide ion
Cyanides
Deprotonation
Ethyl alcohol
Phenol
Pyridines
Pyridyl
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] The selective assay of cyanide ions with a thioamide compound (HNPTU) containing phenol and pyridine as a chemosensor is reported using absorbance changes in a buffered aqueous solution (50mM HEPES, pH 7.4) containing ethanol. Upon treatment with cyanide ions, the colorless solution of HNPTU turned yellow. No significant changes were observed with other comparable anions, such as F−, Cl−, Br−, I−, and CH3COO−. The color change of HNPTU upon treatment with CN− was maintained even in the presence of the comparable monovalent anions. The complex stability constant (Ka=2.6×103) for the stoichiometric 1:1 complexation of HNPTU with cyanide ions was obtained based on absorbance titrations. The interaction of HNPTU with cyanide ions was proposed to be deprotonation, as shown by NMR and Cu(II) treatment experiments.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2014.09.049