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Organocatalytic enantioselective multicomponent cascade reaction: facile access to tetrahydropyridines with C3 all-carbon quaternary stereocenters
A novel organocatalytic asymmetric multicomponent cascade reaction for the synthesis of valuable tetrahydropyridines has been developed. The merit of this cascade process is highlighted by its high efficiency of producing five new bonds and an all-carbon quaternary stereocenter in one operation, whi...
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| Published in: | Tetrahedron 2011-05, Vol.67 (18), p.3273-3277 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c360t-b2609299a76b80cd6faaea518fc403703bba81e39b782a3c5efb224c4b434a033 |
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| cites | cdi_FETCH-LOGICAL-c360t-b2609299a76b80cd6faaea518fc403703bba81e39b782a3c5efb224c4b434a033 |
| container_end_page | 3277 |
| container_issue | 18 |
| container_start_page | 3273 |
| container_title | Tetrahedron |
| container_volume | 67 |
| creator | Yu, De-Feng Wang, Yao Xu, Peng-Fei |
| description | A novel organocatalytic asymmetric multicomponent cascade reaction for the synthesis of valuable tetrahydropyridines has been developed. The merit of this cascade process is highlighted by its high efficiency of producing five new bonds and an all-carbon quaternary stereocenter in one operation, which otherwise is a big challenge to access by traditional strategies.
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| doi_str_mv | 10.1016/j.tet.2011.02.047 |
| format | article |
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| fulltext | fulltext |
| identifier | ISSN: 0040-4020 |
| ispartof | Tetrahedron, 2011-05, Vol.67 (18), p.3273-3277 |
| issn | 0040-4020 1464-5416 |
| language | eng |
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| source | ScienceDirect Journals |
| subjects | Asymmetry Cascade chemical reactions Cascade reactions Cascades Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Multicomponent Organic chemistry Organocatalysis Preparations and properties Quaternary stereocenters Strategy Synthesis (chemistry) Tetrahedrons Tetrahydropyridines |
| title | Organocatalytic enantioselective multicomponent cascade reaction: facile access to tetrahydropyridines with C3 all-carbon quaternary stereocenters |
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