Loading…
Peptidomimetic organocatalysts: efficient Michael addition of ketones onto nitroolefins with very low catalyst loading
The syntheses of two novel peptidomimetic triazole-based organocatalysts that work for the asymmetric conjugate addition of cyclohexanone to nitroolefins are described. The catalysts worked with very low loading (0.5 mol%) in the absence of any additives to provide high diastereo- and enantio-select...
Saved in:
Published in: | RSC advances 2014-01, Vol.4 (57), p.30325-30331 |
---|---|
Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | The syntheses of two novel peptidomimetic triazole-based organocatalysts that work for the asymmetric conjugate addition of cyclohexanone to nitroolefins are described. The catalysts worked with very low loading (0.5 mol%) in the absence of any additives to provide high diastereo- and enantio-selectivities. |
---|---|
ISSN: | 2046-2069 2046-2069 |
DOI: | 10.1039/c4ra04165h |