Antibiotic overuse and Clostridium difficile infections: The Indian paradox and the possible role of dietary practices

Abstract Antibiotic abuse is rampant in India, such that one may expect to see an increase of Clostridium difficile infections (CDI). However, we found that the incidence of CDI in India (1.67%) is no different from that reported in USA (1.6%) using similar techniques of detection (polymerase chain...

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Bibliographic Details
Published in:Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2015-07, Vol.31 (7), p.1052-1053
Main Authors: Ramakrishnan, N., M.D, Sriram, K., M.B.B.S., F.R.C.S.(C)
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - adverse effects
Antibiotic overuse
Antibiotics
Clostridium difficile - growth & development
Clostridium difficile infections
Clostridium Infections - chemically induced
Clostridium Infections - epidemiology
Clostridium Infections - prevention & control
Confidence intervals
Curcuma
Diarrhea - chemically induced
Diarrhea - microbiology
Diarrhea - prevention & control
Dietary fiber
Dietary Fiber - therapeutic use
Gastroenterology and Hepatology
Hospitals
Humans
Incidence
India - epidemiology
Infections
Postpartum period
Probiotics
Risk Factors
Turmeric
Yoghurt
Yogurt
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Summary:Abstract Antibiotic abuse is rampant in India, such that one may expect to see an increase of Clostridium difficile infections (CDI). However, we found that the incidence of CDI in India (1.67%) is no different from that reported in USA (1.6%) using similar techniques of detection (polymerase chain reaction test). We offer a possible explanation for this paradox. It is likely that a diet rich in fiber, yogurt, and possibly turmeric may have a protective role in decreasing the incidence of CDIs in India.
ISSN:0899-9007
1873-1244
DOI:10.1016/j.nut.2015.02.002