Impact of residential medication management reviews on anticholinergic burden in aged care residents

Objectives: The primary objective of this study was to investigate the impact of Residential Medication Management Reviews (RMMRs) on anticholinergic burden quantified by seven anticholinergic risk scales. Design: Retrospective analysis. Setting: Accredited pharmacists conducted RMMRs in aged-care f...

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Bibliographic Details
Published in:Current medical research and opinion 2016-01, Vol.32 (1), p.123-131
Main Authors: McLarin, Patricia E., Peterson, Gregory M., Curtain, Colin M., Nishtala, Prasad S., Hannan, Paul J., Castelino, Ronald L.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aged-care facilities
Anticholinergic burden
Australia
Cholinergic Antagonists - adverse effects
Drug Utilization Review
Female
Homes for the Aged
Humans
Male
Medication reviews
Pharmaceutical Services
Pharmacists
Retrospective Studies
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Summary:Objectives: The primary objective of this study was to investigate the impact of Residential Medication Management Reviews (RMMRs) on anticholinergic burden quantified by seven anticholinergic risk scales. Design: Retrospective analysis. Setting: Accredited pharmacists conducted RMMRs in aged-care facilities (ACFs) in Sydney, Australia. Participants: RMMRs pertained to 814 residents aged 65 years or older. Measurements: Anticholinergic burden was quantified using seven scales at baseline, after pharmacists' recommendations and after the actual GP uptake of pharmacists' recommendations. Change in the anticholinergic burden was measured using the Wilcoxon sign rank test. Results: At baseline, depending on the scale used to estimate the anticholinergic burden, between 36% and 67% of patients were prescribed at least one regular anticholinergic medication (ACM). Anticholinergic burden scores were significantly (p 
ISSN:0300-7995
1473-4877
DOI:10.1185/03007995.2015.1105794