Clozapine-induced tardive dyskinesia: A case report

Clozapine is indicated in the treatment of patients with tardive dyskinesia. However, there have been some reports of movement disorders associated with clozapine treatment in the literature. The authors report a patient who developed tardive dyskinesia 1 year after initiation of clozapine treatment...

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Bibliographic Details
Published in:Progress in neuro-psychopharmacology & biological psychiatry 2005-05, Vol.29 (4), p.633-635
Main Authors: Ertugrul, Aygun, Demir, Basaran
Format: Article
Language:English
Subjects:
Aged
Antipsychotic Agents - adverse effects
Antipsychotic Agents - therapeutic use
Clozapine
Clozapine - adverse effects
Clozapine - therapeutic use
Dyskinesia, Drug-Induced - physiopathology
Humans
Male
Movement disorder
Schizophrenia
Schizophrenia - complications
Schizophrenia - drug therapy
Schizophrenic Psychology
Tardive dyskinesia
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Summary:Clozapine is indicated in the treatment of patients with tardive dyskinesia. However, there have been some reports of movement disorders associated with clozapine treatment in the literature. The authors report a patient who developed tardive dyskinesia 1 year after initiation of clozapine treatment. The patient was a 65-year-old male with diagnosis of schizophrenia who had used multiple typical and atypical antipsychotics for 30 years. Clozapine treatment was initiated for his resistant symptoms. He developed buccolingual dyskinesia of moderate severity, which started 1 year after the initiation of clozapine treatment and did not ameliorate during follow-up. This case may contribute to existing knowledge by raising the possibility that clozapine can induce dyskinesia.
ISSN:0278-5846
1878-4216
DOI:10.1016/j.pnpbp.2005.01.014