The Association of Resting Heart Rate and Incident Hypertension: The Henry Ford Hospital Exercise Testing (FIT) Project

BACKGROUND Given that sympathetic tone is associated with hypertension, we sought to determine whether resting heart rate (RHR), as a surrogate for cardiac autonomic function, was associated with incident hypertension. METHODS We analyzed 21,873 individuals without a history of hypertension who unde...

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Bibliographic Details
Published in:American journal of hypertension 2016-02, Vol.29 (2), p.251-257
Main Authors: Aladin, Amer I., Al Rifai, Mahmoud, Rasool, Shereen H., Keteyian, Steven J., Brawner, Clinton A., Michos, Erin D., Blaha, Michael J., Al-Mallah, Mouaz H., McEvoy, John W.
Format: Article
Language:English
Subjects:
Adult
Exercise Test
Female
Heart Rate
Humans
Hypertension - epidemiology
Hypertension - physiopathology
Incidence
Male
Michigan - epidemiology
Middle Aged
Retrospective Studies
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Summary:BACKGROUND Given that sympathetic tone is associated with hypertension, we sought to determine whether resting heart rate (RHR), as a surrogate for cardiac autonomic function, was associated with incident hypertension. METHODS We analyzed 21,873 individuals without a history of hypertension who underwent a clinically indicated exercise stress test. Baseline RHR was assessed prior to testing and was categorized as 85 beats-per-minute (bpm). Incident hypertension was defined by subsequent diagnosis codes for new-onset hypertension from three or more encounters. We tested for effect modification by age (
ISSN:0895-7061
1941-7225
DOI:10.1093/ajh/hpv095