Health State Utility Impact of Breast Cancer in U.S. Women Aged 18–44 Years

• Published in: American journal of preventive medicine 2016-02, Vol.50 (2), p.255-261
• Main Authors: Brown, Derek S., PhD, Trogdon, Justin G., PhD, Ekwueme, Donatus U., PhD, Chamiec-Case, Linda, BA, Guy, Gery P., PhD, Tangka, Florence K., PhD, Li, Chunyu, MD, PhD, Trivers, Katrina F., PhD, Rodriguez, Juan L., MPH
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Age Factors; Aged; Behavioral Risk Factor Surveillance System; Breast Neoplasms - economics; Breast Neoplasms - epidemiology; Breast Neoplasms - psychology; Cost of Illness; Costs and Cost Analysis; Female; Health Status; Humans; Internal Medicine; Mental Health; Middle Aged; Quality of Life; Socioeconomic Factors; United States - epidemiology; Women's Health; Young Adult
• ISSN: 0749-3797; 1873-2607
• DOI: 10.1016/j.amepre.2015.07.020

Introduction Breast cancer affects women’s health-related quality of life negatively, but little is known about how breast cancer affects this in younger women aged 18–44 years. This study measures preference-based health state utility (HSU) values, a scaled index of health-related quality of life for economic evaluation, for younger women with breast cancer and compares these values with same-age women with other cancers and older women (aged ≥45 years) with breast cancer. Methods Data from the 2009 and 2010 Behavioral Risk Factor Surveillance System were analyzed in 2014. The sample included 218,852 women; 7,433 and 18,577 had histories of breast and other cancers. HSU values were estimated using Healthy Days survey questions and a published mapping algorithm. Linear regression models for HSU were estimated by age group (18–44 and ≥45 years). Results The adjusted breast cancer HSU impact was four times larger for younger women than for older women (–0.097 vs –0.024, p