Temporal Trends in Clinical Outcome After Percutaneous Coronary Intervention 1984–2010　– Report From the Juntendo PCI Registry

Background:Since the introduction of PCI in 1977, it has evolved along with advances in the technology, improvement in operator technique and establishment of medical therapy. However, little is known of the improvement in clinical outcome following PCI.Methods and Results:Data from the Juntendo PCI...

Full description

Saved in:
Bibliographic Details
Published in:Circulation Journal 2015/12/25, Vol.80(1), pp.93-100
Main Authors: Naito, Ryo, Miyauchi, Katsumi, Konishi, Hirokazu, Tsuboi, Shuta, Ogita, Manabu, Dohi, Tomotaka, Kasai, Takatoshi, Tamura, Hiroshi, Okazaki, Shinya, Isoda, Kikuo, Daida, Hiroyuki
Format: Article
Language:English
Subjects:
Age Factors
Aged
Balloon angioplasty
Bare metal stent
Diabetes Complications - mortality
Diabetes Complications - surgery
Disease-Free Survival
Drug-eluting stent
Female
Humans
Japan
Male
Middle Aged
Percutaneous Coronary Intervention - adverse effects
Percutaneous Coronary Intervention - trends
Postoperative Complications - mortality
Prevalence
Registries
Retrospective Studies
Stroke - etiology
Stroke - mortality
Survival Rate
Temporal trend
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background:Since the introduction of PCI in 1977, it has evolved along with advances in the technology, improvement in operator technique and establishment of medical therapy. However, little is known of the improvement in clinical outcome following PCI.Methods and Results:Data from the Juntendo PCI Registry during 1984–2010 were analyzed. The patients were divided into 3 groups according to date of index PCI: POBA era, January 1984–December 1997; BMS era, January 1998–July 2004; and DES era, August 2004–February 2010. The primary endpoint was a composite of MACE including all-cause mortality, non-fatal MI, non-fatal stroke and revascularization. A total of 3,831 patients were examined (POBA era, n=1,147; BMS era, n=1,180; DES era, n=1,504). Mean age was highest in the DES era. The prevalence of diabetes and hypertension was higher in the DES and BMS eras than in the POBA era. Unadjusted cumulative event-free survival rate for 2-year MACE was significantly different across the 3 eras. Adjusted relative risk reduction for 2-year MACE was 56% in the DES era and 34% in the BMS era, both compared with the POBA era. Age, ACS, and LVEF were associated with the incidence of MACE.Conclusions:Clinical outcome of PCI improved across the 26-year study period, despite the higher patient risk profile in the recent era. (Circ J 2016; 80: 93–100)
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-15-0896