Chemical Shift and Fat Suppression Magnetic Resonance Imaging of Thymus in Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune neuromuscular disease leading to fluctuating muscle weakness. Approximately 70% of patients with MG have thymic hyperplasia, and 10-20% of them have thymoma. In MG patients without thymoma, thymectomy should be performed only in selected patients. In contrast,...

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Bibliographic Details
Published in:Canadian journal of neurological sciences 2014-11, Vol.41 (6), p.782-786
Main Authors: Li, Kai, Yang, Da-Wei, Hou, Shi-Fang, Xu, Xian-Hao, Gong, Tao, Chen, Hai-Bo
Format: Article
Language:English
Subjects:
Adipose Tissue - pathology
Adult
Brief Communications
Female
Humans
Magnetic Resonance Imaging - methods
Male
Middle Aged
Myasthenia Gravis - complications
Myasthenia Gravis - diagnosis
Retrospective Studies
Thymoma - complications
Thymoma - diagnosis
Thymus Gland - pathology
Thymus Neoplasms - complications
Thymus Neoplasms - diagnosis
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Summary:Myasthenia gravis (MG) is an autoimmune neuromuscular disease leading to fluctuating muscle weakness. Approximately 70% of patients with MG have thymic hyperplasia, and 10-20% of them have thymoma. In MG patients without thymoma, thymectomy should be performed only in selected patients. In contrast, thymectomy should be performed in all patients wiih thymoma. In addition, thoracoscopic thymectomy can be used in non-thymomatous MG but not in MG with thymoma, since it has limited exposure. Therefore, it is essential to differentiate thymic hyperplasia from thymoma in MG patients so that physicians can determine the need for thymectomy together with the best approach[1] to use.
ISSN:0317-1671
2057-0155
DOI:10.1017/cjn.2014.104