From Unorthodox to Established: The Current Status of (18)F-Trifluoroborate- and (18)F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging

Unorthodox (18)F-labeling strategies not employing the formation of a carbon-(18)F bond are seldom found in radiochemistry. Historically, the formation of a boron- or silicon-(18)F bond has been introduced very early on into the repertoire of labeling chemistries, but is without translation into any...

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Bibliographic Details
Published in:	Bioconjugate chemistry 2016-02, Vol.27 (2), p.267-279
Main Authors:	Bernard-Gauthier, Vadim, Bailey, Justin J, Liu, Zhibo, Wängler, Björn, Wängler, Carmen, Jurkschat, Klaus, Perrin, David M, Schirrmacher, Ralf
Format:	Article
Language:	English
Subjects:	Animals Borates - chemistry Fluorides - chemistry Fluorine Radioisotopes - chemistry Humans Peptides - chemistry Positron-Emission Tomography - methods Radiopharmaceuticals - chemistry Silicon - chemistry Small Molecule Libraries - chemistry
Online Access:	Get full text
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