Balancing Immune Protection and Immune Pathology by CD8+ T-Cell Responses to Influenza Infection

Influenza A virus (IAV) is a significant human pathogen causing annual epidemics and periodic pandemics. CD8(+) cytotoxic T lymphocyte (CTL)-mediated immunity contributes to the clearance of virus-infected cells, and CTL immunity targeting the conserved internal proteins of IAVs is a key protection...

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Bibliographic Details
Published in:	Frontiers in immunology 2016-02, Vol.7, p.25-25
Main Authors:	Duan, Susu, Thomas, Paul G.
Format:	Article
Language:	English
Subjects:	Adaptive immunity Animal models Antibodies Antigens CD8 antigen CD8+ T cells Cells Chemokines Cytokines Cytotoxicity Immune clearance Immune Regulation Immune response Immunity Immunology immunopathology Inflammation Influenza Influenza A Influenza, Human Lymphocytes Lymphocytes T Pandemics Pathogens Pathology RNA polymerase Vaccination Viral infections Viruses Zoonoses
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