Defending a new hypothesis of how bariatric surgery works

A growing body of evidence argues against restriction and malabsorption as key drivers of surgical weight loss as it would contradict findings such as: 1) in rodent models, animals with bariatric surgery are capable of increasing their food intake to meet metabolic needs during pregnancy (2) or afte...

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Bibliographic Details
Published in:Obesity (Silver Spring, Md.) Md.), 2016-03, Vol.24 (3), p.555-555
Main Authors: Frikke‐Schmidt, Henriette, Seeley, Randy J.
Format: Article
Language:English
Subjects:
Bariatric Surgery
Body fat
Food
Gastrointestinal surgery
Humans
Hypotheses
Obesity, Morbid - surgery
Rodents
Weight control
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Summary:A growing body of evidence argues against restriction and malabsorption as key drivers of surgical weight loss as it would contradict findings such as: 1) in rodent models, animals with bariatric surgery are capable of increasing their food intake to meet metabolic needs during pregnancy (2) or after food restriction (3); 2) patients report that they feel less, rather than more, hungry after surgery (4); and 3) appetite regulating gut hormone secretion differs between subjects losing weight by surgery and caloric restriction (5).
ISSN:1930-7381
1930-739X
DOI:10.1002/oby.21444