The epidemic of oesophageal carcinoma: Where are we now?

Highlights • Between 1973 and 2001, oesophageal adenocarcinoma was one of the fastest rising cancers in many developed countries. • Although the rate of increase has slowed, incidence of oesophageal adenocarcinoma continues to rise and will constitute an increasingly large health burden in the years...

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Bibliographic Details
Published in:Cancer epidemiology 2016-04, Vol.41, p.88-95
Main Author: Thrift, Aaron P
Format: Article
Language:English
Subjects:
Adenocarcinoma - epidemiology
Alcohol
Barrett’s oesophagus
Cancer
Carcinoma, Squamous Cell - epidemiology
Cigarettes
Confidence intervals
Conflicts of interest
Disease
Endoscopy
Epidemiology
Esophageal Neoplasms - epidemiology
Ethnicity
Gastro-oesophageal reflux disease
Gastroesophageal Reflux - complications
Health risk assessment
Hematology, Oncology and Palliative Medicine
Humans
Incidence
Internal Medicine
Medical prognosis
Mortality
Nonsteroidal anti-inflammatory drugs
Obesity
Obesity - complications
Oesophageal cancer
Population
Risk Factors
Smoking
Smoking - adverse effects
Surveillance
Trends
Womens health
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Summary:Highlights • Between 1973 and 2001, oesophageal adenocarcinoma was one of the fastest rising cancers in many developed countries. • Although the rate of increase has slowed, incidence of oesophageal adenocarcinoma continues to rise and will constitute an increasingly large health burden in the years ahead. • Men are seven times more likely than women to develop oesophageal adenocarcinoma; the reasons for the striking sex disparity remain unknown. • Gastro-oesophageal reflux disease, obesity and cigarette smoking are the main risk factors for oesophageal adenocarcinoma. • In contrast, the incidence of oesophageal squamous-cell carcinoma continues to decline in Western populations. • 5-year survival rates for oesophageal cancer remain less than 20%.
ISSN:1877-7821
1877-783X
DOI:10.1016/j.canep.2016.01.013