Note: On-chip multifunctional fluorescent-magnetic Janus helical microswimmers

Microswimmers integrated into microfluidic devices that are capable of self-illumination through fluorescence could revolutionize many aspects of technology, especially for biological applications. Few illumination and propulsion techniques of helical microswimmers inside microfluidic channels have...

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Bibliographic Details
Published in:Review of scientific instruments 2016-03, Vol.87 (3), p.036104-036104
Main Authors: Hwang, G., Decanini, D., Leroy, L., Haghiri-Gosnet, A. M.
Format: Article
Language:English
Subjects:
BUBBLES
Channels
DEPOSITION
FABRICATION
FLUIDIC CONTROL DEVICES
FLUORESCENCE
Fluorescent Dyes - chemistry
ILLUMINANCE
Illumination
INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
Lab-On-A-Chip Devices
LASERS
LIQUIDS
Magnetic thin films
Magnets - chemistry
Microfluidics
NANOSTRUCTURES
Nanostructures - chemistry
PHOTONS
Photoresists
PROPULSION
RESOLUTION
Scientific apparatus & instruments
SURFACE TENSION
SURFACES
THIN FILMS
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Summary:Microswimmers integrated into microfluidic devices that are capable of self-illumination through fluorescence could revolutionize many aspects of technology, especially for biological applications. Few illumination and propulsion techniques of helical microswimmers inside microfluidic channels have been demonstrated. This paper presents the fabrication, detachment, and magnetic propulsions of multifunctional fluorescent-magnetic helical microswimmers integrated inside microfluidics. The fabrication process is based on two-photon laser lithography to pattern 3-D nanostructures from fluorescent photoresist coupled with conventional microfabrication techniques for magnetic thin film deposition by shadowing. After direct integration inside a microfluidic device, injected gas bubble allows gentle detachment of the integrated helical microswimmers whose magnetic propulsion can then be directly applied inside the microfluidic channel using external electromagnetic coil setup. With their small scale, fluorescence, excellent resistance to liquid/gas surface tension, and robust propulsion capability inside the microfluidic channel, the microswimmers can be used as high-resolution and large-range mobile micromanipulators inside microfluidic channels.
ISSN:0034-6748
1089-7623
DOI:10.1063/1.4943259