An enzootic outbreak of acute disease associated with pathogenic E. coli in Adler monkey colony

Background In spring 2009 in Adler colony of the Institute of Medical Primatology, a large enzootic outbreak of acute intestine infection associated with pathogenic E. coli occurred and caused 5% mortality of population (209 animals). Methods The epidemiological analysis, bacteriological investigati...

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Bibliographic Details
Published in:Journal of medical primatology 2015-12, Vol.44 (6), p.355-363
Main Authors: Lapin, Boris A., Yakovleva, Lelita A., Dzhikidze, Eteri K., Gvozdik, Tatiana E., Agumava, Aslan A., Stasilevich, Zinaida K., Danilova, Irina G.
Format: Article
Language:English
Subjects:
Animals
Cebus capucinus
Cercopithecus aethiops
colibacillosis
Disease Outbreaks - veterinary
enterohemorrhagic E. coli
enteroinvasive E. coli
enteropathogenic E. coli
Enteropathogenic Escherichia coli - isolation & purification
enzootic outbreak
Escherichia coli
Escherichia coli Infections - epidemiology
Escherichia coli Infections - microbiology
Escherichia coli Infections - veterinary
Haplorhini
hemorrhagic enterocolitis
Housing, Animal
intestine infection
Monkey Diseases - epidemiology
Monkey Diseases - microbiology
Russia - epidemiology
Time Factors
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Summary:Background In spring 2009 in Adler colony of the Institute of Medical Primatology, a large enzootic outbreak of acute intestine infection associated with pathogenic E. coli occurred and caused 5% mortality of population (209 animals). Methods The epidemiological analysis, bacteriological investigation, postmortem examination, histological analysis, and PCR were used to identify the infectious agent. Results Marked hemorrhagic diathesis, lethargy, dehydration, diarrhea with blood, wasting, and sometimes dystrophic changes in articular cartilages were noted. Morphologically, hemorrhagic enterocolitis and massive hemorrhages were found. PCR investigation of bacteriologically isolated E. coli characterized it as enteropathogenic and enteroinvasive E. coli. Conclusions The outbreak in Adler colony slightly differed from similar outbreak in Florida in 2014 by more marked hemorrhagic diathesis and articular changes in some monkeys caused by polyavitaminosis developed in the course of infection. Sensitive to infection were M. mulatta, M. fascicularis, Cercopithecus aethiops, P. hamadryas and anubis, and Cebus capucinus.
ISSN:0047-2565
1600-0684
DOI:10.1111/jmp.12184